Senior Operations Manager, Business Systems & Integrations

Death is our only foe. Immortals was founded by Bryan Johnson and Kate Tolo to build a new standard for human health and longevity. We’re building Autonomous Health: a system that uses measurement, scientific evidence, and personalization to help people understand their bodies and make better decisions about their health. What began with Bryan becoming the most measured person in history is becoming a platform for everyone. Immortals brings together biomarkers, longevity medicine, nutrition, prescriptions, wearables, and personalized protocols in one place, turning health data into clear, actionable decisions. We’re a small, ambitious team building what we believe will become the new operating system for human health. We move quickly, think from first principles, care deeply about the quality of our work, and hold ourselves to an unusually high standard. Our mission is simple: help billions of people live healthier lives for longer, and ultimately, Don’t Die. This role plays a critical role in ensuring Blueprint’s operational systems, inventory flows, and commercial execution scale cleanly as the business grows. This role acts as a control point across operational systems, middleware, fulfillment partners, and commercial channels, partnering closely with Operations, Supply Chain, E-commerce, Customer Service, and external vendors. This is a highly hands-on role focused on execution, systems integrity, and problem-solving, ideal for someone who thrives in fast-moving environments and enjoys turning complex workflows into clean, repeatable processes. Requirements Position Responsibilities: Systems Ownership & Integrations Own the day-to-day performance, configuration, and continuous improvement of the operational systems ecosystem, including NetSuite, middleware, warehouse management systems (WMS), and other connected operational platforms. Ensure integrations and data flows operate reliably across systems and support end-to-end business processes. Serve as the operational owner for system workflows and integrations, partnering with internal teams and external technology providers to investigate issues, resolve exceptions, and coordinate solutions. Lead root-cause analysis for integration failures, data mismatches, and process breakdowns, addressing underlying issues and preventing recurrence. Maintain visibility into system dependencies, workflows, and data movement across platforms. Identify opportunities to improve system configuration, streamline integrations, and reduce manual intervention while ensuring systems can scale with business needs. Order Management, Inventory & Operational Execution Manage end-to-end operational workflows across DTC, Amazon, retail, wholesale, B2B, and international channels, ensuring accurate execution from order placement through inventory allocation, fulfillment, and financial reconciliation. Partner closely with the Ecommerce team on Shopify-related workflows and integrations without owning the Shopify platform. Own operational setup and maintenance of items and SKUs in NetSuite and connected systems, ensuring accurate product data and system configuration. Support new product launches, SKU transitions, product lifecycle changes, out-of-stock and end-of-life workflows, and other updates that affect inventory availability, order processing, or customer experience. Partner with Supply Chain, Finance, and fulfillment providers to maintain inventory accuracy across NetSuite, middleware, and 3PL systems. Investigate and resolve inventory discrepancies, order exceptions, transaction mismatches, and reconciliation issues, including inventory transfers, allocations, kitting and de-kitting, and other workflows that affect operational and financial records. Support EDI requirements and the system workflows needed to serve retail and wholesale partners. Coordinate with internal stakeholders and external partners to troubleshoot order transmission, inventory synchronization, fulfi…

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