Senior Manager, Strategic R&D Partnerships & Program Operations

Location: Cambridge, MA

This role is based in Cambridge, MA, with hybrid flexibility. On-site presence is prioritized for onboarding and key collaboration moments. Marengo values outcomes, accountability, and an environment where high performers thrive.

Company Overview

Marengo Therapeutics is a Phase 2 clinical-stage immuno-oncology company developing first-in-class immune activators designed to precisely stimulate and expand anti-tumor T cells to drive deep, durable anti-tumor immunity. The company has a rich pipeline of multi-specific therapeutics powered by three different platforms supported by advanced antibody discovery and immunology insights. The company’s lead STAR program is progressing in the clinic across multiple solid tumor indications

Marengo’s scientific platform and development strategy are further validated through multiple strategic partnerships with large-cap global pharmaceutical companies, reflecting the industry’s confidence in the novelty and potential impact of Marengo’s approach.

Position Summary

Marengo seeks a Senior Manager, Strategic R&D Partnerships & Program Operations—a high-impact role at the intersection of preclinical program operations, scientific communication, and business strategy. The ideal candidate combines operational rigor with scientific fluency and can translate complex R&D work into clear narratives for internal and external stakeholders.

Key Responsibilities

Program & Project Operations:

• Build and maintain program plans, timelines/milestones, risks, dependencies, and decision logs across multiple early research and preclinical initiatives.
• Drive meeting cadence (agendas, minutes, follow-ups), ensuring cross-functional alignment and accountability.
• Surface risks/bottlenecks early and coordinate mitigation plans.

Cross-Functional Scientific & Strategic Support:

• Synthesize scientific and operational updates into concise materials for leadership review and decision-making.
• Contribute to portfolio roll-ups, scenario planning, and prioritization discussions.
• Help bring structure and clarity to complex, fast-moving workstreams.

External-Facing Support:

• Prepare partner-ready materials (scientific summaries, briefing docs, meeting notes) and support high-quality external engagement.
• Learn and apply fundamentals of partner governance and expectations; uphold a professional, solutions-oriented tone.
• Draft first-pass content for external updates (e.g., PR input, website copy) and scientific narratives tailored to diverse audiences.
• Translate technical content into clear, accurate, and compelling communication.

Qualifications

Required

• 4–8 years of experience in biotech/pharma or closely related life sciences roles.
• Advanced scientific degree (PhD or MS strongly preferred) or demonstrated scientific fluency.
• Meaningful exposure to business strategy / BD operations / competitive intelligence / corporate communications or IR (e.g., building decks, data rooms, diligence materials, press inputs, external updates).
• Demonstrated capability in cross-functional project or program management.
• Excellent written and verbal communication; strong stakeholder management; high ownership.

Preferred

• Experience in early-stage drug development (research, preclinical, translational).
• Exposure to CRO/vendor coordination and partner-facing interactions.
• Track record of operating effectively in dynamic, high-expectation environments.

Who You Are

• A fast learner who asks smart questions and takes initiative.
• Clear, concise, and confident in communication—internally and externally.
• Highly organized with strong follow-through; comfortable with ambiguity.
• Motivated by impact and energized by a broad scope of work and growth opportunities.