Manager - Sample Management Operations

At Caris, we understand that cancer is an ugly word—a word no one wants to hear, but one that connects us all. That’s why we’re not just transforming cancer care—we’re changing lives. We introduced precision medicine to the world and built an industry around the idea that every patient deserves answers as unique as their DNA. Backed by cutting-edge molecular science and AI, we ask ourselves every day: “What would I do if this patient were my mom?” That question drives everything we do. But our mission doesn’t stop with cancer. We're pushing the frontiers of medicine and leading a revolution in healthcare—driven by innovation, compassion, and purpose. Join us in our mission to improve the human condition across multiple diseases. If you're passionate about meaningful work and want to be part of something bigger than yourself, Caris is where your impact begins. Position Summary The Sample Management Operations Manager provides leadership, operational oversight, and technical expertise for the Sample Management function, ensuring the integrity, efficiency, scalability, and compliance of specimen management operations supporting laboratory, research, and organizational initiatives. This position serves as both a people leader and working manager, actively supporting day-to-day specimen management activities while leading the continued evolution of the Sample Management operation. The Manager is responsible for overseeing the complete lifecycle management of remnant biological specimens following diagnostic testing, including specimen receipt, inventory management, storage, retrieval, request fulfillment, de-identification, distribution, disposition, and chain of custody. Leveraging previous experience in specimen management operations, this role identifies opportunities to strengthen workflows, optimize Laboratory Information Management System (LIMS) utilization, implement industry best practices, and improve operational efficiency to support organizational growth. Working collaboratively with Laboratory Operations, Clinical Operations, Research, Quality, Information Technology, and other cross-functional stakeholders, the Manager develops a high-performing team, drives continuous improvement initiatives, and helps build a scalable, customer-focused Sample Management operation while ensuring compliance with applicable regulatory and organizational requirements. Job Responsibilities Leadership & Team Development. Lead, coach, and develop the Sample Management team by providing day-to-day leadership, technical guidance, performance management, and professional development while fostering a culture of accountability, collaboration, customer service, quality, and continuous improvement. Sample Management Operations. Provide operational oversight of the complete lifecycle management of remnant biological specimens following diagnostic testing, including specimen receipt, inventory management, storage, retrieval, request fulfillment, transfer, distribution, de-identification, and disposition. Serve as a working manager by supporting complex specimen management activities, resolving escalated operational issues, and ensuring specimen integrity and chain of custody throughout the specimen lifecycle. Inventory, Logistics & Resource Management. Oversee specimen inventory, storage capacity, environmental monitoring, logistics, retrieval, transfers, and distribution while ensuring inventory accuracy, efficient utilization of resources, and operational readiness to support current and future business needs. Data Management & Technology Optimization. Ensure the integrity of specimen data within Laboratory Information Management Systems (LIMS) and Sample Management Systems while driving optimization of workflows, reporting, inventory visibility, system utilization, and operational technologies to improve efficiency and scalability. Quality Assurance & Regulatory Compliance. Lead quality assur…

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