Vice President, Tax

Revolution Medicines is a global, commercial-state oncology company dedicated to discovering, developing and delivering innovative medicines for patients with RAS-addicted cancers. Leveraging its differentiated RAS(ON) tri-complex inhibitor platform, the company is advancing a broad, integrated portfolio of oral RAS(ON) inhibitors designed to directly target the active, cancer-driving state of RAS. Founded on rigorous scientific inquiry and a willingness to challenge long-held assumptions, Revolution Medicines is committed to changing the trajectory of disease for patients with RAS-addicted cancers worldwide. Our people are united by a shared way of working: follow the science, challenge assumptions, act with urgency and hold ourselves to a high standard of rigor—all in service of patients. The Opportunity: Lead RevMed's global tax function, owning strategy, operating model, governance, and execution across planning, financial reporting, compliance, and audits. Align tax priorities with long-term corporate strategy, supporting OUS commercial readiness, international expansion, and sustainable growth while protecting financial position and reputation. Act as trusted advisor to senior leadership: translate complex tax matters into clear business choices and anticipate risks and opportunities. Build a scalable tax organization and develop leaders, partnering with Finance, Legal, and the business while staying hands-on in critical judgments and execution. The role reports to Vice President of Finance and will represent Tax in front of the Audit Committee and senior executives. Responsibilities Global Tax Strategy and Enterprise Partnership Set and own the global tax strategy and multiyear roadmap, aligning priorities, investment, and outcomes with corporate goals, capital needs, and growth. Advise senior leadership on tax implications of strategic decisions (cash taxes, financial reporting, feasibility, compliance, reputation); escalate significant exposures to senior executives and, as appropriate, the Audit Committee. Lead tax planning for corporate structure, financing, IP, licensing, collaborations, and transactions; partner with Legal, Treasury, Business Development, and Finance on diligence, structuring, and implementation. Anticipate global tax changes, assess enterprise impact, and lead coordinated responses; establish tax policies, decision rights, and escalation thresholds. International Expansion and Transfer Pricing Own tax strategy and readiness for new markets with Global Finance and Legal (entity structures, registrations, operating models, transition to local support). Lead global transfer pricing policy, intercompany pricing, documentation, and governance, aligned with business substance, IP, supply chain, and local requirements. Partner with Commercial, Supply Chain, Treasury, and others on income tax, indirect tax, tariffs, withholding, and permanent establishment issues in cross-border operations. Tax Accounting and Financial Reporting Own quality, accuracy, and timeliness of global quarterly and annual provisions under US GAAP, including ASC 740 judgments, deferred taxes, valuation allowances, uncertain tax positions, and disclosures. Oversee the Integration of tax into the close, forecasts, long-range plans, and cash planning with Corporate Accounting, SEC Reporting, FP&A, and Treasury; explain effective tax rate drivers and material changes. Ultimate owner of tax accounting policies, documentation, and SOX controls; lead external auditor engagement on significant positions and resolve complex reporting matters. Compliance, Risk Management, and Tax Audits Oversee global tax team that manages global compliance across US federal, state, and international obligations; define responsibilities with Payroll, Legal, local Finance, Supply Chain and service providers. Maximize tax attributes and incentives (R&D credits, NOLs). Lead audits, inquiries, and disputes; represent RevMed with tax authorities and adviso…

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