Senior Manager Manufacturing – Night Shift Operations Performance & Integration
AmgenUS - Ohio - New Albany JOB ID: R-258233 LOCATION: US - Ohio - New Albany WORK LOCATION TYPE: On Site DATE POSTED: Oct. 15, 2026 CATEGORY: Manufacturing SALARY RANGE: 136,227.80USD -184,308.20 USD Join Amgen’s Mission of Serving Patients At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. Amgen is advancing a broad and deep pipeline and portfolio of medicines to treat heart disease, obesity and obesity-related conditions, rare diseases, inflammatory conditions and cancer. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Night Senior Manager Manufacturing – Night Operations Performance & Integration (Continuous Improvement) What you will do Let’s do this. Let’s change the world. In this vital role the Night Shift Senior Manager of Manufacturing at Amgen is responsible for establishing and sustaining a strong night-shift operating system that provides off-shift operational direction for Commercial Operations and for Project based Commissioning and Qualification (C&Q) coverage, ensuring the right cross-functional resources are engaged, issues are escalated and resolved with urgency, and manufacturing performance is actively managed across the shift. Partners with Engineering, Automation, QA, Technology, Maintenance, Supply Chain/Warehouse, Capital Projects. Responsibilities Serve as the senior Manufacturing integration point across night-shift operations during significant operational events. Establish and sustain the night-shift Tier structure, operating cadence, escalation model, and performance-management routines. Coordinate Manufacturing, Quality Assurance, Engineering, Automation, Maintenance, Supply Chain/Warehouse, and other site resources required to maintain safe, compliant, and reliable operations. Drive escalation of significant resource constraints, technical barriers, competing priorities, or unresolved operational issues to appropriate site or functional leadership. Monitor overall night-shift Manufacturing performance across production lines, including downtime, OEE, schedule attainment, recurring interruptions, escalation effectiveness, and chronic losses. Partner with the daytime Manufacturing Senior Manager, Continuous Improvement Senior Manager and MFG process Support Senior Manager to identify, prioritize, and execute improvement opportunities across off-shift, including 5S, visual management, standard work, workplace organization, waste reduction, flow improvement, and training operating discipline. Provide coaching and situational leadership to Front Line Managers during complex operational events What we expect of you We are all different, yet we all use our unique contributions to serve patients. The professional we seek will possess these qualifications. Basic Qualifications: Doctorate degree and 2 years in GMP manufacturing, process development, or combination device, and/or manufacturing focused six sigma lean operational excellence. OR Master’s degree and 6 years in GMP manufacturing, process development, or combination device, and/or manufacturing focused six sigma lean operational excellence. OR Bachelor’s degree and 8 years in GMP manufacturing, process development, or combination device, and/or manufacturing focused six sigma lean operational excellence. OR Associate’s d…