Senior Manager, DNA Manufacturing Operations & Integration

The Role: Joining Moderna means advancing mRNA science to transform medicine. Work with exceptional global teams on a broad pipeline and build a career that makes a real difference for patients. Moderna is strengthening its presence in Norwood, Massachusetts, a cornerstone of our manufacturing and operational excellence. Our Norwood campus translates mRNA science into scalable impact, supporting the global delivery of our medicines. We welcome talent ready to drive innovation and make a meaningful difference for patients worldwide. This is an opportunity to lead at the intersection of DNA Manufacturing, Cell Bank operations, Operational Excellence, technology transfer, quality, digital capability, and manufacturing performance, helping translate complex technical and business priorities into reliable execution. You will lead a highly capable team while owning the continuous improvement agenda for DNA Manufacturing, using operational data, structured problem solving, and cross-functional leadership to identify risks, unlock capacity, strengthen processes, and deliver sustainable improvements. As a member of the DNA Leadership Team, you will influence priorities beyond your immediate function, solve complex and ambiguous challenges across organizational boundaries, and help build the manufacturing capabilities, culture, and digital ways of working needed for the next stage of Moderna’s operations. Here’s What You’ll Do: Lead, develop, and coach a team of Specialists and Senior Specialists with broad expertise across DNA and Cell Bank manufacturing processes, building a highly capable and adaptable team that can address evolving operational priorities. Own and continuously improve the DNA Manufacturing continuous improvement and Operational Excellence program, including the identification, prioritization, execution, and benefits realization of improvement opportunities. Lead complex, cross-functional initiatives spanning DNA Manufacturing and partner organizations, establishing clear objectives, governance, execution plans, decision-making mechanisms, and accountability for delivery. Own the strategy and execution of manufacturing change controls associated with area improvements, ensuring changes are effectively planned, assessed, implemented, embedded, and sustained within manufacturing operations. Provide manufacturing leadership and execution support for technology transfers, serving as the Manufacturing representative, coordinating manufacturing readiness activities, and providing project management across cross-functional teams to enable successful transfer and execution. Lead the use of operational data, performance indicators, manufacturing trends, and operational insights to proactively identify emerging risks, improvement opportunities, capacity constraints, and priorities for DNA Operations. Establish and continuously evolve effective operational performance management mechanisms, including dashboards, routine performance reviews, action tracking, and escalation processes for emerging issues. Serve as a GMP leader and manufacturing subject matter expert, providing support for investigations, operational events, risk assessments, change implementation, and other quality system activities as required. Partner closely with Manufacturing Science & Technology (MSAT), Quality Assurance, Supply Chain, Digital, CMC Development, Planning, and other stakeholders to integrate technical, quality, supply, and business priorities into effective manufacturing execution. Support the organization’s ongoing state of inspection readiness, ensuring the team, processes, documentation, change activity, and improvements within the role’s scope are prepared to effectively support regulatory inspections. Build organizational capability in continuous improvement, structured problem solving, project execution, data-driven decision making, and change management, strengthening the organization’s ability to respo…

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