Senior Manager, Cell Therapy Hub

Location Wilmington, Delaware, United States Job ID R-263379 Date posted 02/11/2026 At AstraZeneca, we follow the science to explore and innovate, working to treat, prevent, modify, and ultimately cure some of the world's most complex diseases. Within our Cell Therapy organization, we are advancing cutting-edge science and technology to transform outcomes for patients with cancer. We are seeking a Senior Manager, Cell Therapy Hub to join our Cell Therapy Patient Operations team supporting clinical and commercial cell therapy production across multiple sites. This field-based role serves as a critical connection point between treatment centers, healthcare professionals, patients, and AstraZeneca cross-functional teams, ensuring a seamless vein-to-vein (V2V) patient journey. The successful candidate will demonstrate expertise in patient coordination, provider support, and cell therapy operations while delivering an exceptional experience for treatment sites and patients. Reporting to the Senior Director, Cell Therapy Hub, this position plays a key role in advancing life-changing cell therapy treatments through operational excellence and patient-centered support. As the Senior Manager, Cell Therapy Hub, you will: Serve as a trusted, knowledgeable single point of contact for treatment site collaborators, improving the site experience through the AstraZeneca Cell Therapy Hub. Independently manage all patient vein-to-vein workflows from patient registration through infusion within assigned geographic regions. Identify, raise, and resolve patient-related issues while providing coverage support across regions as needed. Partner closely with cross-functional teams including Clinical Operations, Site Management, Supply Chain, Medical Affairs, Information Technology, Commercial, and other team members to meet patient and healthcare provider needs. Communicate critical patient-related information to site collaborators with empathy and professionalism while managing expectations. Collaborate with Regional and Territory Operations Managers to ensure site logistics, personnel readiness, and Chain of Identity (COI)/Chain of Custody (COC) access to AstraZeneca digital platforms. Coordinate communication and resolution of issues related to cellular starting materials, investigational medicinal products (IMPs), and associated supplies. Partner with Quality Assurance, Manufacturing, and Supply Chain teams on out-of-specification (OOS) communications, product recalls, and product-related site issues. Develop and maintain internal and external standard operating procedures (SOPs), training materials, and operational documentation related to the Cell Therapy Hub. Demonstrate proficiency in all Cell Therapy Hub systems, including Customer Portal and telephony platforms, as well as associated SOPs, work instructions, and business processes. Drive continuous improvement initiatives and contribute to the development of innovative solutions that enhance the patient care experience. Maintain compliance with AstraZeneca policies, regulatory standards, and Cell Therapy Hub procedures. Support implementation and rollout of process improvements and operational changes across assigned treatment sites. Demonstrate a strong commitment to patients by consistently reflecting AstraZeneca values in daily interactions and decision-making. Perform other duties as assigned while maintaining adherence to applicable regulations and SOPs. Travel greater than 50% as required. Essential Skills/Experience Bachelor's degree in Life Sciences, Healthcare, Nursing, Business, or a related field, or equivalent combination of education and experience. Minimum of 4 years of experience within a cell therapy program, healthcare system, or regulated healthcare environment in roles such as: Research Coordinator Nurse Coordinator Apheresis Nurse Cell Laboratory Professional Quality Manager Other patient-focused cell therapy or oncology operational roles Experience managing complex patien…

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