Manager, Technical Operations

ModeX Therapeutics, an OPKO Health company, is the leading clinical-stage biopharmaceutical company developing unique and proprietary multispecific therapeutics. Its MSTAR platform unites the power of multiple biologics in a single molecule to create multispecific antibodies that bind four or more targets with unprecedented versatility and potency for complex diseases. Its promising first-in-class immunology pipeline includes candidates against immune diseases, including cancer (both solid and hematologic tumors), immune impairment, as well as several of the world's most pressing viral threats. Its founding team includes globally recognized medical innovators with proven track records of delivering breakthroughs for patients. ModeX is based in Weston, Massachusetts. For more information, please visit www.modextx.com. Job Summary The Manager, Technical Operations provides operational leadership for CMC development and clinical supply activities across global development programs. This individual serves as the functional owner for key Technical Operations outsourced and in-house processes, including stability and supply chain activities, while driving cross-functional alignment among internal and external stakeholders. The role is responsible for operational planning and execution including risk management and continuous improvement initiatives that support the successful CMC development and supply of clinical-stage products. This is a manager-level individual contributor position requiring strong technical judgment, commitment to quality, and the ability to influence outcomes. The ideal candidate is highly organized, detail-oriented, data-driven, and committed to operational excellence and accuracy. Why Join Us? In this job you will play a pivotal role in advancing innovative biologic therapies from development through clinical execution. This is an opportunity to build and lead stability and clinical supply strategies that directly influence product development, regulatory milestones, and patient access to investigational therapies. What Makes This Role Unique High-impact decision making Lead stability programs, shelf-life assessments, and clinical supply strategies that directly influence development timelines and clinical trial success. Use scientific and operational judgment to guide critical decisions on inventory utilization, expiration dating, and supply continuity. Broad visibility and influence Partner closely with senior leaders across CMC, Quality, Regulatory Affairs, Clinical Operations, and external development partners. Present recommendations and risk assessments that shape program strategy and business decisions. Ownership across the product lifecycle Drive stability and clinical supply activities from early clinical development through late-stage programs. Lead initiatives spanning analytical testing, stability studies, packaging, labeling, global distribution, and inventory management. Work on innovative therapies Support cutting-edge biologic development programs addressing significant unmet patient needs. Contribute to complex development challenges involving novel modalities, cold-chain logistics, and global clinical supply networks. A collaborative and entrepreneurial environment Join a growing organization where expertise, initiative, and problem-solving are highly valued. Work in a highly cross-functional setting where individuals are empowered to make meaningful contributions and drive change. Professional growth Expand your technical and strategic leadership capabilities through exposure to multiple development programs, regulatory interactions, and global clinical operations. Build a foundation for future leadership opportunities across Technical Operations, CMC, Supply Chain, and Product Development. Who Will Thrive Here This role is ideal for candidates who enjoy combining scientific rigor with operational leadership, are energized by solving complex development challenges, and want to make a visibl…

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