Associate Director, Clinical Supply Chain Planning

Revolution Medicines is a global, commercial-state oncology company dedicated to discovering, developing and delivering innovative medicines for patients with RAS-addicted cancers. Leveraging its differentiated RAS(ON) tri-complex inhibitor platform, the company is advancing a broad, integrated portfolio of oral RAS(ON) inhibitors designed to directly target the active, cancer-driving state of RAS. Founded on rigorous scientific inquiry and a willingness to challenge long-held assumptions, Revolution Medicines is committed to changing the trajectory of disease for patients with RAS-addicted cancers worldwide. Our people are united by a shared way of working: follow the science, challenge assumptions, act with urgency and hold ourselves to a high standard of rigor—all in service of patients. The Opportunity: Collaborating with product leads and study managers, will ensure global clinical demand for RevMed and Non Rev-Med commercial products is accurately reflected within the N-side system on a monthly basis as part of DnOP process. Drive business process standardization, implementation, and training on new processes. Lead end-to-end clinical supply planning for assigned clinical programs and studies, from study start-up through closeout. Support the development of global clinical supply strategies aligned with clinical protocols, enrollment assumptions, dosing regimens, country activation plans, and program timelines. Build and maintain clinical supply forecasts, translating clinical demand into manufacturing, packaging, labeling, distribution, and inventory requirements. Develop scenario analyses and supply models to evaluate enrollment changes, dose modifications, cohort expansions, geographic changes, and other protocol or operational assumptions. Establish appropriate inventory and safety-stock strategies to maintain continuity of supply while minimizing waste, obsolescence, and expiry risk. Monitor inventory levels, consumption, enrollment trends, expiry dates, and other supply indicators and proactively identify potential shortages or excess inventory. Drive continuous improvement of clinical supply planning processes, systems, metrics, and ways of working. Contribute to performance management, budgeting, and long-range clinical supply planning. Provide guidance and subject-matter expertise to colleagues and cross-functional partners on clinical supply planning and execution. Required Skills, Experience and Education: Bachelor’s degree in Supply Chain, Life Sciences, Engineering, Business, or a related discipline; advanced degree preferred. Typically 8+ years of relevant experience in pharmaceutical or biotechnology supply chain, including substantial experience supporting clinical-stage programs. Demonstrated experience independently managing clinical supply planning for complex, global clinical studies. Oncology experience preferred. Strong understanding of clinical development and the clinical supply lifecycle, including forecasting, manufacturing planning, packaging and labeling, distribution, depot management, inventory management, and returns/reconciliation. Experience developing demand forecasts and scenario models based on enrollment, dosing, treatment duration, randomization, site activation, and other clinical assumptions. N-side forecasting tool experience. Working knowledge of IRT/RTSM systems and their role in clinical supply management. Understanding of GMP/GDP requirements and relevant regulatory expectations governing clinical trial materials. Demonstrated ability to identify supply risks, evaluate tradeoffs, and develop practical mitigation strategies in a dynamic clinical development environment. Strong analytical, organizational, and problem-solving skills with attention to detail and the ability to manage multiple studies and competing priorities. Excellent communication and stakeholder-management skills, with demonstrated ability to influence cross-functional teams without direct authority. Ability to…

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