Supervisor, Cell Culture Operations (Hopewell, NJ)

BeOne continues to grow at a rapid pace with challenging and exciting opportunities for experienced professionals. When considering candidates, we look for scientific and business professionals who are highly motivated, collaborative, and most importantly, share our passionate interest in fighting cancer.

General Description:

Reporting to the Head of DS Manufacturing Cell Culture. This position plays a leading role in troubleshooting processes, building a detailed understanding of them, and driving process robustness and meeting manufacturing timelines by setting clear objectives and empowering their team. This position involves consistent collaboration with Cell Culture MSAT, DS Manufacturing Purification, Facilities & Engineering, Quality Control, Quality Assurance, Regulatory groups.

This position requires through knowledge in mammalian cell culture processes and some exposure to protein purification and protein product quality attributes. Of equal importance is the ability to lead and develop reports.

Essential Functions of the Job:

• Leading, mentoring and development of staff is a critical part of the responsibility, with an aim to empower team members to a level commensurate with their skills and experience.

• Participate in cross-functional projects teams

• Ensure a safe working environment

• Effective communication with team members and stakeholders is a must

• Participate in and support on-site supervision and management of contract manufacturers as required by BeiGene.

Technical Skills/Knowledge:

• CIP & SIP of fixed stainless-steel vessels and transfer lines

• Solution preparation and transfer

• Single Use Technologies (mixers & bioreactors)

• Seed lab operations: passaging and scale-up

• Bioreactor wave and shaker flask

• Bioreactor operations

• Harvest operations

• Sterile Filtration / Integrity testing

• Analytical Instrumentation (pH, osmometer etc.)

• Good Documentation Practices

• Equipment and process troubleshooting

• Authoring SOP’s, MBR’s & WI’s

• Delivering technical presentations

• Quality Risk Assessments

• Health Authority Interaction/Audits

• Resource Modeling

• OE and/or LEAN Methodologies

• Distributed Control system / Control Systems

• Deviations, assessments, investigations & CAPA’s

• SAP, LIMS, CMMS, Veeva

Education / Experience Required:

• BA/BS or higher in science, biochemistry, biotechnology, biology, chemical engineering and/or related discipline.

• Minimum of 2+ years of experience in the Life Science/Biotechnology.

• Minimum of 1+ years supervisory experience in biopharma industry

• Knowledge of GMP & GDP drug preclinical, clinical and commercial requirements.

• Familiarity with EMA and FDA regulatory requirements.

• Effective communication, oral and written, in a multi-disciplinary, project-driven work environment. 

Supervisory Responsibilities:  

• Strategic and tactical planning with ability to convey business relevance to team

• Ability to translate strategy into actionable goals and expectations for team members  

• Consistently delivers tangible business that support organizational objectives via self and direct reports

• Leading, directing, coaching/developing, and providing timely feedback to direct reports

• Planning and managing day to day activities, including staff availability and task load

• Writing and delivering effective performance appraisals

• Consistently receives and provides feedback thoughtfully

• Self-directed leadership within both predicable and ambiguous work environments

• Inclusive and cross-functional collaboration with all levels

• Ability to cultivate culture of continuous improvement and right first-time quality

• Thoughtfully escalates issues/concerns in a timely manner as appropriate

• Project management and working through competing priorities

• Recruiting, interviewing, and selecting key talent

Computer Skills:

• Strong PC literacy required; MS Office skills (Outlook, Word, Excel, PowerPoint).

Other Qualifications:

• N/A

Travel:  Some travel may occur as a result of duties assigned to the role, up to 20%

Global Competencies

When we exhibit our values of Patients First, Driving Excellence, Bold Ingenuity and Collaborative Spirit, through our twelve global competencies below, we help get more affordable medicines to more patients around the world.

• Fosters Teamwork
• Provides and Solicits Honest and Actionable Feedback
• Self-Awareness
• Acts Inclusively
• Demonstrates Initiative
• Entrepreneurial Mindset
• Continuous Learning
• Embraces Change
• Results-Oriented
• Analytical Thinking/Data Analysis
• Financial Excellence
• Communicates with Clarity

BeOne is committed to fair and equitable compensation practices. Actual compensation packages are determined by several factors that are unique to each candidate, including but not limited to job-related skills, depth of experience, certifications, relevant education or training, and specific work location. Packages may vary by location due to differences in the cost of labor. The recruiter can share more about the specific salary range for a preferred location during the hiring process.  Please note that the listed range reflects the base salary or hourly range only. Non-Commercial roles are eligible to participate in the annual bonus plan, and Commercial roles are eligible to participate in an incentive compensation plan. All Company employees have the opportunity to own shares of BeOne Medicines Ltd. stock because all employees are eligible for discretionary equity awards and to voluntarily participate in the Employee Stock Purchase Plan. The Company has a comprehensive benefits package that includes Medical, Dental, Vision, 401(k), FSA/HSA, Life Insurance, Paid Time Off, and Wellness.

We are proud to be an equal opportunity employer. BeOne does not discriminate on the basis of race, religion, color, sex, gender identity, sexual orientation, age, disability, national origin, veteran status or any other basis covered by appropriate law. All employment is decided on the basis of qualifications, merit, and business need. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans’ Readjustment Assistance Act of 1974, Title I of the Americans with Disabilities Act of 1990, and any other applicable federal, state or local laws, applicants who require reasonable accommodation in the job application process may contact accommodationsus@beonemed.com.